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Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells

BACKGROUND: Pancreatic cancer is a complex genetic disorder that is characterized by rapid progression, invasiveness, resistance to treatment and high molecular heterogeneity. Various agents have been used in clinical trials showing only modest improvements with respect to gemcitabine-based chemothe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kreutzer, Jan N, Ruzzene, Maria, Guerra, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931491/
https://ncbi.nlm.nih.gov/pubmed/20718998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-440
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