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Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells

BACKGROUND: Pancreatic cancer is a complex genetic disorder that is characterized by rapid progression, invasiveness, resistance to treatment and high molecular heterogeneity. Various agents have been used in clinical trials showing only modest improvements with respect to gemcitabine-based chemothe...

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Detalhes bibliográficos
Main Authors: Kreutzer, Jan N, Ruzzene, Maria, Guerra, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931491/
https://ncbi.nlm.nih.gov/pubmed/20718998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-440
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