Expansion and maintenance of human embryonic stem cell–derived endothelial cells by TGFβ inhibition is Id1 dependent

Previous efforts to differentiate human embryonic stem cells (hESCs) into endothelial cells have not achieved sustained expansion and stability of vascular cells. To define vasculogenic developmental pathways and enhance differentiation, we used an endothelial cell–specific VE-cadherin promoter driv...

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Bibliographische Detailangaben
Hauptverfasser: James, Daylon, Nam, Hyung-song, Seandel, Marco, Nolan, Daniel, Janovitz, Tyler, Tomishima, Mark, Studer, Lorenz, Lee, Gabsang, Lyden, David, Benezra, Robert, Zaninovic, Nikica, Rosenwaks, Zev, Rabbany, Sina Y, Rafii, Shahin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931334/
https://ncbi.nlm.nih.gov/pubmed/20081865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1605
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