Expansion and maintenance of human embryonic stem cell–derived endothelial cells by TGFβ inhibition is Id1 dependent

Previous efforts to differentiate human embryonic stem cells (hESCs) into endothelial cells have not achieved sustained expansion and stability of vascular cells. To define vasculogenic developmental pathways and enhance differentiation, we used an endothelial cell–specific VE-cadherin promoter driv...

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Detalhes bibliográficos
Main Authors: James, Daylon, Nam, Hyung-song, Seandel, Marco, Nolan, Daniel, Janovitz, Tyler, Tomishima, Mark, Studer, Lorenz, Lee, Gabsang, Lyden, David, Benezra, Robert, Zaninovic, Nikica, Rosenwaks, Zev, Rabbany, Sina Y, Rafii, Shahin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931334/
https://ncbi.nlm.nih.gov/pubmed/20081865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1605
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