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Human anti–HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness
The identification and characterization of conserved epitopes on the HIV-1 viral spike that are immunogenic in humans and targeted by neutralizing antibodies is an important step in vaccine design. Antibody cloning experiments revealed that 32% of all HIV-neutralizing antibodies expressed by the mem...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2931156/ https://ncbi.nlm.nih.gov/pubmed/20679402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101176 |
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