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Enhanced HIV-1 neutralization by antibody heteroligation

Passive transfer of broadly neutralizing human antibodies against HIV-1 protects macaques against infection. However, HIV-1 uses several strategies to escape antibody neutralization, including mutation of the gp160 viral surface spike, a glycan shield to block antibody access to the spike, and expre...

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Detalhes bibliográficos
Main Authors: Mouquet, Hugo, Warncke, Malte, Scheid, Johannes F., Seaman, Michael S., Nussenzweig, Michel C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271928/
https://ncbi.nlm.nih.gov/pubmed/22219363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120059109
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