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An environmental DNA-derived type II polyketide biosynthetic pathway encodes the biosynthesis of the novel pentacyclic polyketide, erdacin
Environmental DNA-derived cosmid clones containing type II polyketide synthase genes were screened for the ability to produce clone-specific metabolites in Streptomyces. One of the Streptomyces recombinants produces erdacin, a novel polyketide with a previously unknown pentacyclic skeleton. Erdacin...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930765/ https://ncbi.nlm.nih.gov/pubmed/19621341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200901209 |
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