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Allosteric Block of K(Ca)2 Channels by Apamin

Activation of small conductance calcium-activated potassium (K(Ca)2) channels can regulate neuronal firing and synaptic plasticity. They are characterized by their high sensitivity to the bee venom toxin apamin, but the mechanism of block is not understood. For example, apamin binds to both K(Ca)2.2...

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Detalhes bibliográficos
Main Authors: Lamy, Cédric, Goodchild, Samuel J., Weatherall, Kate L., Jane, David E., Liégeois, Jean-François, Seutin, Vincent, Marrion, Neil V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930706/
https://ncbi.nlm.nih.gov/pubmed/20562108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.110072
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