Wird geladen...

Inhibition of K(Ca)2.2 and K(Ca)2.3 channel currents by protonation of outer pore histidine residues

Ion channels are often modulated by changes in extracellular pH, with most examples resulting from shifts in the ionization state of histidine residue(s) in the channel pore. The application of acidic extracellular solution inhibited expressed K(Ca)2.2 (SK2) and K(Ca)2.3 (SK3) channel currents, with...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Goodchild, Samuel J., Lamy, Cedric, Seutin, Vincent, Marrion, Neil V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757770/
https://ncbi.nlm.nih.gov/pubmed/19786583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910252
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!