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Inhibition of K(Ca)2.2 and K(Ca)2.3 channel currents by protonation of outer pore histidine residues
Ion channels are often modulated by changes in extracellular pH, with most examples resulting from shifts in the ionization state of histidine residue(s) in the channel pore. The application of acidic extracellular solution inhibited expressed K(Ca)2.2 (SK2) and K(Ca)2.3 (SK3) channel currents, with...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757770/ https://ncbi.nlm.nih.gov/pubmed/19786583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910252 |
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