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Control of voltage-gated K(+) channel permeability to NMDG(+) by a residue at the outer pore
Crystal structures of potassium (K(+)) channels reveal that the selectivity filter, the narrow portion of the pore, is only ∼3-Å wide and buttressed from behind, so that its ability to expand is highly constrained, and the permeation of molecules larger than Rb(+) (2.96 Å in diameter) is prevented....
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699102/ https://ncbi.nlm.nih.gov/pubmed/19332619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810139 |
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