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Control of voltage-gated K(+) channel permeability to NMDG(+) by a residue at the outer pore

Crystal structures of potassium (K(+)) channels reveal that the selectivity filter, the narrow portion of the pore, is only ∼3-Å wide and buttressed from behind, so that its ability to expand is highly constrained, and the permeation of molecules larger than Rb(+) (2.96 Å in diameter) is prevented....

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Bibliografski detalji
Glavni autori: Wang, Zhuren, Wong, Nathan C., Cheng, Yvonne, Kehl, Steven J., Fedida, David
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699102/
https://ncbi.nlm.nih.gov/pubmed/19332619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810139
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