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Allosteric coupling of the inner activation gate to the outer pore of a potassium channel
In potassium channels, functional coupling of the inner and outer pore gates may result from energetic interactions between residues and conformational rearrangements that occur along a structural path between them. Here, we show that conservative mutations of a residue near the inner activation gat...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3806241/ https://ncbi.nlm.nih.gov/pubmed/24149575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03025 |
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