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Voltage Clamp Fluorimetry Reveals a Novel Outer Pore Instability in a Mammalian Voltage-gated Potassium Channel

Voltage-gated potassium (Kv) channel gating involves complex structural rearrangements that regulate the ability of channels to conduct K(+) ions. Fluorescence-based approaches provide a powerful technique to directly report structural dynamics underlying these gating processes in Shaker Kv channels...

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Detalles Bibliográficos
Autores principales: Vaid, Moninder, Claydon, Thomas W., Rezazadeh, Saman, Fedida, David
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483330/
https://ncbi.nlm.nih.gov/pubmed/18625849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200809978
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