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SOX9, through Interaction with Microphthalmia-associated Transcription Factor (MITF) and OTX2, Regulates BEST1 Expression in the Retinal Pigment Epithelium
BEST1 is highly and preferentially expressed in the retinal pigment epithelium (RPE) and causes Best macular dystrophy when mutated. We previously demonstrated that the human BEST1 upstream region −154 to +38 bp is sufficient to direct expression in the RPE of transgenic mice, and microphthalmia-ass...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930693/ https://ncbi.nlm.nih.gov/pubmed/20530484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.130294 |
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