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BEST1 expression in the retinal pigment epithelium is modulated by OTX family members

A number of genes preferentially expressed in the retinal pigment epithelium (RPE) are associated with retinal degenerative disease. One of these, BEST1, encodes bestrophin-1, a protein that when mutated causes Best macular dystrophy. As a model for RPE gene regulation, we have been studying the mec...

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Hlavní autoři: Esumi, Noriko, Kachi, Shu, Hackler, Laszlo, Masuda, Tomohiro, Yang, Zhiyong, Campochiaro, Peter A., Zack, Donald J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605189/
https://ncbi.nlm.nih.gov/pubmed/18849347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn323
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