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Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners
Vitamin K epoxide reductase (VKOR) sustains blood coagulation by reducing vitamin K epoxide to the hydroquinone, an essential cofactor for the γ-glutamyl carboxylation of many clotting factors. The physiological redox partner of VKOR remains uncertain, but is likely a thioredoxin-like protein. Here,...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930587/ https://ncbi.nlm.nih.gov/pubmed/20696932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009972107 |
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