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Structure of a bacterial homolog of vitamin K epoxide reductase

Vitamin K epoxide reductase (VKOR) generates vitamin K hydroquinone to sustain γ-carboxylation of many blood coagulation factors. Here, we report the 3.6Å crystal structure of a bacterial homolog of VKOR from Synechococcus sp. The structure shows VKOR in complex with its naturally fused redox partne...

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Détails bibliographiques
Auteurs principaux: Li, Weikai, Schulman, Sol, Dutton, Rachel J., Boyd, Dana, Beckwith, Jon, Rapoport, Tom A.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919313/
https://ncbi.nlm.nih.gov/pubmed/20110994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08720
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