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Membrane Topology and Mutational Analysis of Mycobacterium tuberculosis VKOR, a Protein Involved in Disulfide Bond Formation and a Homologue of Human Vitamin K Epoxide Reductase

We have presented evidence that a homologue of vertebrate membrane protein vitamin K epoxide reductase (VKOR) is an important component of the protein disulfide bond-forming pathway in many bacteria. Bacterial VKOR appears to take the place of the nonhomologous DsbB found in Escherichia coli. We als...

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Bibliographic Details
Main Authors: Wang, Xiaoyun, Dutton, Rachel J., Beckwith, Jon, Boyd, Dana
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061198/
https://ncbi.nlm.nih.gov/pubmed/20969481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3558
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