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Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Krüppel-like factor
Studies of mouse models of anemia have long provided fundamental insights into red blood cell formation and function. Here we show that the semidominant mouse mutation Nan (“neonatal anemia”) carries a single amino acid change (E339D) within the second zinc finger of the erythroid Krüppel-like facto...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930539/ https://ncbi.nlm.nih.gov/pubmed/20696915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004996107 |
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