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Funnel sculpting for in silico assembly of secondary structure elements of proteins

We present a method for designing a funnel-shaped free-energy surface that reproducibly assembles secondary structure elements of proteins into their native conformations from a random extended configuration. Assuming a priori knowledge of secondary structure, our method can design a funnel-shaped s...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Fain, Boris, Levitt, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC293046/
https://ncbi.nlm.nih.gov/pubmed/12925740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1732312100
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