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Funnel sculpting for in silico assembly of secondary structure elements of proteins
We present a method for designing a funnel-shaped free-energy surface that reproducibly assembles secondary structure elements of proteins into their native conformations from a random extended configuration. Assuming a priori knowledge of secondary structure, our method can design a funnel-shaped s...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC293046/ https://ncbi.nlm.nih.gov/pubmed/12925740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1732312100 |
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