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Electrostatic effects on funneled landscapes and structural diversity in denatured protein ensembles
The denatured state of proteins is heterogeneous and susceptible to general hydrophobic and electrostatic forces, but to what extent does the funneled nature of protein energy landscapes play a role in the unfolded ensemble? We simulate the denatured ensemble of cytochrome c using a series of models...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2644117/ https://ncbi.nlm.nih.gov/pubmed/19181849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813120106 |
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