NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain

Increasing evidence supports the notion that spinal cord microglia activation plays a causal role in the development of neuropathic pain after peripheral nerve injury; yet the mechanisms for microglia activation remain elusive. Here, we provide evidence that NADPH oxidase 2 (Nox2)-derived ROS produc...

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Hlavní autoři: Kim, Donghoon, You, Byunghyun, Jo, Eun-Kyeong, Han, Sang-Kyou, Simon, Melvin I., Lee, Sung Joong
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930447/
https://ncbi.nlm.nih.gov/pubmed/20679217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009926107
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