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Toll-like Receptor 2 Mediates Peripheral Nerve Injury-induced NADPH Oxidase 2 Expression in Spinal Cord Microglia

We have previously reported that NADPH oxidase 2 (Nox2) is up-regulated in spinal cord microglia after spinal nerve injury, demonstrating that it is critical for microglia activation and subsequent pain hypersensitivity. However, the mechanisms and molecules involved in Nox2 induction have not been...

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Detalhes bibliográficos
Main Authors: Lim, Hyoungsub, Kim, Donghoon, Lee, Sung Joong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597798/
https://ncbi.nlm.nih.gov/pubmed/23386616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.414904
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