Iron accentuated reactive oxygen species release by NADPH oxidase in activated microglia contributes to oxidative stress in vitro

BACKGROUND: Excessive iron contributes to oxidative stress after central nervous system injury. NADPH oxidase (NOX) enzymes are upregulated in microglia after pro-inflammatory activation and contribute to oxidative stress. The relationship between iron, microglia, NOX, and oxidative stress is curren...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Yauger, Young J., Bermudez, Sara, Moritz, Kasey E., Glaser, Ethan, Stoica, Bogdan, Byrnes, Kimberly R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378754/
https://ncbi.nlm.nih.gov/pubmed/30777083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1430-7
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