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Divergent effects of low-O(2) tension and iloprost on ATP release from erythrocytes of humans with type 2 diabetes: implications for O(2) supply to skeletal muscle

Erythrocytes release both O(2) and a vasodilator, ATP, when exposed to reduced O(2) tension. We investigated the hypothesis that ATP release is impaired in erythrocytes of humans with type 2 diabetes (DM2) and that this defect compromises the ability of these cells to stimulate dilation of resistanc...

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Main Authors: Sprague, Randy S., Goldman, Daniel, Bowles, Elizabeth A., Achilleus, David, Stephenson, Alan H., Ellis, Christopher G., Ellsworth, Mary L.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2010
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930397/
https://ncbi.nlm.nih.gov/pubmed/20511412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00430.2010
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