A selective phosphodiesterase 3 inhibitor rescues low Po(2)-induced ATP release from erythrocytes of humans with type 2 diabetes: implication for vascular control

Erythrocytes, via release of ATP in areas of low oxygen (O(2)) tension, are components of a regulatory system for the distribution of perfusion in skeletal muscle ensuring optimal O(2) delivery to meet tissue needs. In type 2 diabetes (DM2), there are defects in O(2) supply to muscle as well as a fa...

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Detaylı Bibliyografya
Asıl Yazarlar: Sprague, Randy S., Bowles, Elizabeth A., Achilleus, David, Stephenson, Alan H., Ellis, Christopher G., Ellsworth, Mary L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2011
Konular:
Integrative Cardiovascular Physiology and Pathophysiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233804/
https://ncbi.nlm.nih.gov/pubmed/21963837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00729.2011
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