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Diamide Decreases Deformability of Rabbit Erythrocytes and Attenuates Low Oxygen Tension-Induced ATP Release

Exposure of erythrocytes to reduced oxygen (O(2)) tension activates the heterotrimeric G protein Gi, resulting in accumulation of cAMP and release of ATP. The mechanism by which exposure of erythrocytes to reduced O(2) tension activates Gi is not known. Here we investigate the hypothesis that, in ra...

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Autors principals: Sridharan, Meera, Sprague, Randy S., Adderley, Shaquria P., Bowles, Elizabeth A., Ellsworth, Mary L., Stephenson, Alan H.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138790/
https://ncbi.nlm.nih.gov/pubmed/20682601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2010.010118
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