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Synthesis and evaluation of antimigratory and antiproliferative activities of lipid-linked [13]-macro-dilactones

The biological activities of a family of novel, lipid-linked 13-membered-ring macro-dilactones are reported. These [13]-macro-dilactones were synthesized by diacylation of functionalized diols, followed by ring-closing metathesis under conditions we had previously reported. Antimigratory, cytostatic...

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Bibliografische gegevens
Hoofdauteurs: Magpusao, Anniefer N., Desmond, Richard T., Billings, Katelyn J., Fenteany, Gabriel, Peczuh, Mark W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930117/
https://ncbi.nlm.nih.gov/pubmed/20709546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.07.083
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