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De novo macrolide–glycolipid macrolactone hybrids: Synthesis, structure and antibiotic activity of carbohydrate-fused macrocycles

Natural product-like macrocycles were designed as potential antibacterial compounds. The macrocycles featured a D-glucose unit fused into a 12- or 13-member macrolactone. The rings are connected via the C6’ and anomeric (C1’) positions of the monosaccharide. The new macrocycles/macrolides were chara...

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Библиографические подробности
Главные авторы: Desmond, Richard T, Magpusao, Anniefer N, Lorenc, Chris, Alverson, Jeremy B, Priestley, Nigel, Peczuh, Mark W
Формат: Artigo
Язык:Inglês
Опубликовано: Beilstein-Institut 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168945/
https://ncbi.nlm.nih.gov/pubmed/25246980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.229
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