Antiproliferative and Antimigratory Effects of a Novel YAP–TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking

[Image: see text] The Hippo pathway is an important regulator of cell growth, proliferation, and migration. TEAD transcription factors, which lie at the core of the Hippo pathway, are essential for regulation of organ growth and wound repair. Dysregulation of TEAD and its regulatory cofactor Yes-ass...

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Bibliografske podrobnosti
izdano v:J Med Chem
Main Authors: Smith, Sarah A., Sessions, Richard B., Shoemark, Deborah K., Williams, Christopher, Ebrahimighaei, Reza, McNeill, Madeleine C., Crump, Matthew P., McKay, Tristan R., Harris, Gemma, Newby, Andrew C., Bond, Mark
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2019
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701825/
https://ncbi.nlm.nih.gov/pubmed/30640473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.8b01402
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