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Crystal structure of human adenovirus at 3.5 Å resolution
Rational development of adenovirus vectors for therapeutic gene transfer is hampered by the lack of accurate structural information. Here we report the X-ray structure at 3.5 Å resolution of the 150 megadalton adenovirus capsid containing nearly 1 million amino acids. We describe interactions betwee...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929978/ https://ncbi.nlm.nih.gov/pubmed/20798318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1187292 |
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