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Crystal structure of AcrB complexed with linezolid at 3.5 Å resolution
AcrB is an inner membrane resistance-nodulation-cell division efflux pump and is part of the AcrAB–TolC tripartite efflux system. We have determined the crystal structure of AcrB with bound Linezolid at a resolution of 3.5 Å. The structure shows that Linezolid binds to the A385/F386 loops of the sym...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679416/ https://ncbi.nlm.nih.gov/pubmed/23673416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10969-013-9154-x |
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