In vivo endotoxin synchronizes and suppresses clock gene expression in human peripheral blood leukocytes

OBJECTIVES: The intravenous administration of a bolus dose of endotoxin to healthy human subjects triggers acute systemic inflammatory responses that include cytokine production and dynamic changes in gene expression in peripheral blood leukocytes (PBL). This study sought to determine the state of c...

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Bibliographic Details
Main Authors: Haimovich, Beatrice, Calvano, Jacqueline, Haimovich, Adrian D., Calvano, Steve E., Coyle, Susette M., Lowry, Stephen F.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929957/
https://ncbi.nlm.nih.gov/pubmed/20081528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3181cd131c
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