A novel model of common Toll-like receptor 4- and injury-induced transcriptional themes in human leukocytes

INTRODUCTION: An endotoxin challenge, sepsis, and injury/trauma, trigger significant changes in human peripheral blood leukocytes (PBL) gene expression. In this study, we have sought to test the hypothesis that the Toll-like receptor 4 (TLR4) induced transcription patterns elicited in humans exposed...

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Autors principals: Haimovich, Beatrice, Reddell, Michael T, Calvano, Jacqueline E, Calvano, Steve E, Macor, Marie A, Coyle, Susette M, Lowry, Stephen F
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219281/
https://ncbi.nlm.nih.gov/pubmed/20929567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc9283
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