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In vivo endotoxin synchronizes and suppresses clock gene expression in human peripheral blood leukocytes

OBJECTIVES: The intravenous administration of a bolus dose of endotoxin to healthy human subjects triggers acute systemic inflammatory responses that include cytokine production and dynamic changes in gene expression in peripheral blood leukocytes (PBL). This study sought to determine the state of c...

詳細記述

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書誌詳細
主要な著者: Haimovich, Beatrice, Calvano, Jacqueline, Haimovich, Adrian D., Calvano, Steve E., Coyle, Susette M., Lowry, Stephen F.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929957/
https://ncbi.nlm.nih.gov/pubmed/20081528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3181cd131c
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