Steroid production and Excretion by the pregnant mouse, particularly in relation to pregnancies with fetuses deficient in Δ(7)-sterol reductase (Dhcr7), the enzyme associated with Smith-Lemli-Opitz syndrome

This study has shown that the mouse has a great increase in steroid production during pregnancy in similar fashion to the human. Many steroids were provisionally identified in maternal urine of the wild-type mouse. The major progesterone metabolites appear to be hydroxylated pregnanolones, particula...

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Bibliographic Details
Main Authors: Matabosch, Xavier, Rahman, Mahbuba, Hughes, Beverly, Patel, Shailendra B., Watson, Gordon, Shackleton, Cedric
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929956/
https://ncbi.nlm.nih.gov/pubmed/19406241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2009.04.011
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