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Hair and skin sterols in normal mice and those with deficient dehydrosterol reductase (DHCR7), the enzyme associated with Smith-Lemli-Opitz syndrome

Our recent studies have focused on cholesterol synthesis in mouse models for 7-dehydrosterolreductase (DHCR7) deficiency, also known as Smith-Lemli-Opitz syndrome. Investigations of such mutants have relied on tissue and blood levels of the cholesterol precursor 7-dehydrocholesterol (7DHC) and its 8...

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Bibliografiska uppgifter
Huvudupphovsmän: Serra, Montserrat, Matabosch, Xavier, Ying, Lee, Watson, Gordon, Shackleton, Cedric
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964438/
https://ncbi.nlm.nih.gov/pubmed/20804844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2010.08.006
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