Cancer Stem Cells Contribute to Cisplatin Resistance in Brca1/p53–Mediated Mouse Mammary Tumors

The majority of BRCA1-associated breast cancers are basal cell–like, which is associated with a poor outcome. Using a spontaneous mouse mammary tumor model, we show that platinum compounds, which generate DNA breaks during the repair process, are more effective than doxorubicin in Brca1/p53–mutated...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Shafee, Norazizah, Smith, Christopher R., Wei, Shuanzeng, Kim, Yoon, Mills, Gordon B., Hortobagyi, Gabriel N., Stanbridge, Eric J., Lee, Eva Y-H. P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929908/
https://ncbi.nlm.nih.gov/pubmed/18451150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5480
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC2929908/
https://ncbi.nlm.nih.gov/pubmed/18451150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5480

Gelijkaardige items