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New players in the sepsis-protective activated protein C pathway

Recombinant activated protein C (aPC) improves the survival of patients with severe sepsis, but the precise molecular and cellular targets through which it mediates this effect remain incompletely understood. In this issue of the JCI, Kerschen et al. show that endothelial cell protein C receptor (EP...

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Bibliografiske detaljer
Hovedforfatter: Ruf, Wolfram
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929744/
https://ncbi.nlm.nih.gov/pubmed/20714106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44266
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