טוען...

cAMP-activated Ca(2+) signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways

Cystic fibrosis (CF), which is caused by mutations in CFTR, affects many tissues, including the lung. Submucosal gland serous acinar cells are primary sites of fluid secretion and CFTR expression in the lung. Absence of CFTR in these cells may contribute to CF lung pathogenesis by disrupting fluid s...

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מידע ביבליוגרפי
Main Authors: Lee, Robert J., Foskett, J. Kevin
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929731/
https://ncbi.nlm.nih.gov/pubmed/20739756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42992
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