Forced unfolding modulated by disulfide bonds in the Ig domains of a cell adhesion molecule

Cell adhesion molecules (CAMs) mediate cell attachment and stress transfer through extracellular domains. Here we forcibly unfold the Ig domains of a prototypical Ig superfamily CAM that contains intradomain disulfide bonds. The Ig domains of all such CAMs have conformations homologous to cadherin e...

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Bibliografiske detaljer
Main Authors: Carl, Philippe, Kwok, Carol H., Manderson, Gavin, Speicher, David W., Discher, Dennis E.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC29297/
https://ncbi.nlm.nih.gov/pubmed/11171991
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