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Forced Unfolding of Coiled-Coils in Fibrinogen by Single-Molecule AFM
Fibrinogen is a blood plasma protein that, after activation by thrombin, assembles into fibrin fibers that form the elastic network of blood clots. We used atomic force microscopy to study the forced unfolding of engineered linear oligomers of fibrinogen, and we show that forced extension of the oli...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1796812/ https://ncbi.nlm.nih.gov/pubmed/17172299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.101261 |
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