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Multiscale Mechanics of Fibrin Polymer: Gel Stretching with Protein Unfolding and Loss of Water

Blood clots and thrombi consist primarily of a mesh of branched fibers made of the protein fibrin. We propose a molecular basis for the marked extensibility and negative compressibility of fibrin gels based on the structural and mechanical properties of clots at the network, fiber, and molecular lev...

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Bibliografiske detaljer
Main Authors: Brown, André E. X., Litvinov, Rustem I., Discher, Dennis E., Purohit, Prashant K., Weisel, John W.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846107/
https://ncbi.nlm.nih.gov/pubmed/19661428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1172484
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