SOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNA

Reactive oxygen species (ROSs) are produced during normal cellular metabolism, particularly by respiration in mitochondria, and these ROSs are considered to cause oxidative damage to macromolecules, including DNA. In our previous paper, we found no indication that depletion of mitochondrial superoxi...

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Detalhes bibliográficos
Main Authors: Inoue, Eri, Tano, Keizo, Yoshii, Hanako, Nakamura, Jun, Tada, Shusuke, Watanabe, Masami, Seki, Masayuki, Enomoto, Takemi
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929635/
https://ncbi.nlm.nih.gov/pubmed/20811569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/795946
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