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Determinants of Affinity and Activity of the Anti-Sigma Factor AsiA

The AsiA protein is a T4 bacteriophage early gene product that regulates transcription of host and viral genes. Monomeric AsiA binds tightly to the σ(70) subunit of Escherichia coli RNA polymerase, thereby inhibiting transcription from bacterial promoters and phage early promoters and co-activating...

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Detalhes bibliográficos
Main Authors: Gilmore, Joshua M., Urbauer, Ramona J. Bieber, Minakhin, Leonid, Akoyev, Vladimir, Zolkiewski, Michal, Severinov, Konstantin, Urbauer, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929534/
https://ncbi.nlm.nih.gov/pubmed/20545305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1002635
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