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Ethanol enhances taurine-activated glycine receptor function

BACKGROUND: Emerging evidence suggests that taurine acts as a partial agonist at glycine receptors (GlyR) in vitro and in vivo. Ethanol acts as an allosteric modulator at the GlyR producing a leftward shift of the glycine concentration-response curve, with no enhancing effects observed at saturating...

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Main Authors: Welsh, Brian T., Kirson, Dean, Allen, Hunter M., Mihic, S. John
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929299/
https://ncbi.nlm.nih.gov/pubmed/20586750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2010.01249.x
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