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Loss of p19(Arf) Facilitates the Angiogenic Switch and Tumor Initiation in a Multi-Stage Cancer Model via p53-Dependent and Independent Mechanisms

The Arf tumor suppressor acts as a sensor of oncogenic signals, countering aberrant proliferation in large part via activation of the p53 transcriptional program, though a number of p53-independent functions have been described. Mounting evidence suggests that, in addition to promoting tumorigenesis...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ulanet, Danielle B., Hanahan, Douglas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929208/
https://ncbi.nlm.nih.gov/pubmed/20805995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012454
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