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CREB Inhibits AP-2α Expression to Regulate the Malignant Phenotype of Melanoma
BACKGROUND: The loss of AP-2α and increased activity of cAMP-responsive element binding (CREB) protein are two hallmarks of malignant progression of cutaneous melanoma. However, the molecular mechanism responsible for the loss of AP-2α during melanoma progression remains unknown. METHODOLOGY/PRINCIP...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929203/ https://ncbi.nlm.nih.gov/pubmed/20805990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012452 |
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