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Silencing cAMP-response Element-binding Protein (CREB) Identifies CYR61 as a Tumor Suppressor Gene in Melanoma

Metastatic progression of melanoma is associated with overexpression and activity of cAMP-response element-binding protein (CREB). However, the mechanism by which CREB contributes to tumor progression and metastasis remains unclear. Here, we demonstrate that stably silencing CREB expression in two h...

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Autors principals: Dobroff, Andrey S., Wang, Hua, Melnikova, Vladislava O., Villares, Gabriel J., Zigler, Maya, Huang, Li, Bar-Eli, Menashe
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758018/
https://ncbi.nlm.nih.gov/pubmed/19632997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019836
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