Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase

Eukaryotic cells require iron for survival and have developed regulatory mechanisms for maintaining appropriate intracellular iron concentrations. The degradation of iron regulatory protein 2 (IRP2) in iron-replete cells is a key event in this pathway, but the E3 ubiquitin ligase responsible for its...

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Detalhes bibliográficos
Main Authors: Vashisht, Ajay A., Zumbrennen, Kimberly B., Huang, Xinhua, Powers, David N., Durazo, Armando, Sun, Dahui, Bhaskaran, Nimesh, Persson, Anja, Uhlen, Mathias, Sangfelt, Olle, Spruck, Charles, Leibold, Elizabeth A., Wohlschlegel, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929180/
https://ncbi.nlm.nih.gov/pubmed/19762596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1176333
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